Animal experiments show that BL21 can effectively reduce blood sugar levels in diabetic mice, improve the antioxidant capacity of the livers, repair intestinal barrier damage, reduce inflammatory reactions, and improve intestinal flora disorders in diabetic mice. At the same time, the combined use of BL21 with Lactiplantibacillus plantarum Lp90, Lactiplantibacillus plantarum CW006, Lactiplantibacillus plantarum N13 and Pediococcus acidilactis CCFM7902 can effectively regulate the body's blood sugar metabolism and alleviate the symptoms of hyperglycemia.

Has good gastrointestinal fluid tolerance and intestinal adhesion ability, can reach the intestines and adhere to intestinal epithelial cells smoothly. Animal experiments show that WKB148 can effectively inhibit pathogenic bacteria such as Shigella flexneri and increase the relative abundance of beneficial bacteria in the intestines of mice.

It has good tolerance to gastric juice and bile salts, and also has proteolytic activity. It can metabolize and produce angiotensin-converting enzyme inhibitory peptide to achieve anti-hypertensive effects.

It has a strong inhibitory effect on the growth of Listeria monocytogenes, can inhibit the growth of common pathogenic bacteria, increase the number of beneficial bacteria, and regulate intestinal flora.