SCI/Patent Supported
Potency
300B CFU/g
Source of Strain
Healthy infant intestines
Deposit Number
PTA-126829(ATCC) No.21801(CGMCC)
[1]Zhu M, Zhu J, Fang S, Zhao B. Complete genome sequence of Heyndrickxia (Bacillus) coagulans BC99 isolated from a fecal sample of a healthy infant. Microbiol Resour Announc. 2024 Jan 17;13(1):e0044923. doi: 10.1128/mra.00449-23. Epub 2023 Dec 14. PMID: 38095439; PMCID: PMC10793334.
[2]Wu Y, Bai Z, Jin Y, Zhu H, Dong Y, Gu S and Jin Y (2024) A randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of Weizmannia coagulans BC99 in the treatment of chronic constipation in adults.Front. Nutr. 11:1395083.doi: 10.3389/fnut.2024.1395083。PMID:39119466
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Apply BC99 into the preparation of colitis relief products or immunomodulatory productsBC99 can regulate the intestinal immune function of mice and significantly reduce the pro-inflammatory factor TNF in thecolon tissue of mice-a. The content of lL-6 significantly increases the content of anti-inflammatory factor lL-10.