Bifidobacterium animalis subsp. lactis BLa80 alleviates the risk of obesity

There are 200 million overweight people in China

More than 90 million people are obese

Diseases such as high cholesterol and non-alcoholic fatty liver disease caused by overweight and obesity

Increasing year by year and showing a younger trend

High cholesterol and non-alcoholic fatty liver disease are harmful to human health

High cholesterol is more likely to cause metabolic abnormalities

and other diseases such as hypertension, coronary heart disease, cardiovascular and cerebrovascular diseases, etc.

Non-alcoholic fatty liver disease can also easily lead to fatty cirrhosis and even liver cancer.

BLa80 helps alleviate the risk of obesity

Wecare Probiotics Bifidobacterium animalis subsp. lactis BLa80 has a significant cholesterol-lowering effect and can alleviate the increase in high cholesterol caused by high-fat diet; at the same time, Bifidobacterium animalis subsp. lactis BLa80 compound probiotic (Bifidobacterium animalis subsp. lactis BLa80+ Lactobacillus rhamnosus LRa05 + Lactobacillus plantarum Lp90) can alleviate the symptoms of non-alcoholic fatty liver disease and weight changes caused by high-fat diet.

Experimental Study

Mitigating cholesterol changes caused by high-fat diet

14 weeks of high-fat diet caused a significant increase in total cholesterol (TC) in the serum of rats. The BLa80+LRa05+Lp90 compound probiotic intervention could significantly reduce the TC content in the rat serum, indicating that the BLa80 compound probiotic has the ability to relieve high blood pressure. Increased cholesterol due to fatty diet.

BLa80 alone also has a significant cholesterol-lowering effect. The results above show that 14 days of high-fat diet caused a significant increase in total cholesterol (TC) in the serum of mice. After intervention with BLa80, the TC content in the serum of mice increased significantly. Decreased, indicating that BLa80 has the effect of alleviating the increase in cholesterol caused by high-fat diet.

Relieve symptoms of non-alcoholic fatty liver disease caused by high-fat diet

High-fat diet can cause liver disease. Rats in the high-fat diet group showed obvious symptoms of non-alcoholic fatty liver disease (NALFD), including obvious liver cell swelling, ballooning, intralobular necrosis and inflammatory cells, causing NALFD scores. The BLa80+LRa05+Lp90 compound probiotic intervention can reduce the degree of steatosis and inflammatory cell infiltration, and reduce the NALFD score.

Alleviate weight changes caused by high-fat diet

Starting from the second week of the high-fat diet, the weight of the rats increased significantly faster than that of the normal rats, and throughout the intervention period, the weight of the rats on the high-fat diet showed a gradual increase trend. After the intervention of BLa80+LRa05+Lp90 compound probiotics, the weight of rats decreased significantly from the tenth week and was significantly lower than that of the high-fat diet group, indicating that BLa80+LRa05+Lp90 compound probiotics can alleviate the weight loss caused by high-fat diet. Among them, Lactobacillus plantarum Lp90 can inhibit fat accumulation and has the potential effect of preventing obesity.

Analysis conclusion

Wecare Probiotics Bifidobacterium animalis subsp. lactis BLa80 possesses powerful bile salt hydrolase activity, which makes it excellent in lowering cholesterol. Studies have shown that this strain has a high cholesterol removal rate and can significantly reduce serum cholesterol levels. In addition, Bifidobacterium animalis subsp. lactis BLa80 compound powder (BLa80+LRa05+Lp90 compound probiotic) also shows good potential in alleviating high cholesterol, non-alcoholic fatty liver symptoms and weight changes caused by high-fat diet . Therefore, Bifidobacterium animalis subsp. lactis BLa80 and compound bacterial powder (BLa80+LRa05+Lp90 compound probiotic) have broad application prospects in the preparation of prevention and treatment of obesity.