Probiotic Solutions for Anti-Hangover and Delicate Liver Protection

According to statistics, the drinking population in China accounts for 33.8% of the total population (approximately 470 million people), with 26% (approximately 123 million people) being excessive drinkers.

65% of people engage in unhealthy drinking habits, consuming more than 40 grams of alcohol daily for over 5 years. Among them, 48% will suffer from varying degrees of alcoholic liver disease. For individuals who have been drinking continuously for 8 years, with a daily average alcohol consumption of 227 grams, 33% will develop alcoholic hepatitis, and 14% will develop alcoholic cirrhosis. The number of deaths in China caused by alcohol-related conditions reaches as high as 410,000 annually. With the increasing number of drinkers, alcohol-induced liver damage diseases are on the rise.

The China Alcoholic Drinks Association has released the "2020 Blue Book on Moderate Drinking for a Happy Life" and more.

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Probiotic Solution for Hangover Liver Protection

Patented Star Strains for Enhanced Effects

To address the issue of alcohol-induced liver damage, Wecare Probiotics has launched a composite powder solution combining multiple patented star strains, including Bacillus coagulans BC99, Pediococcus pentosaceus PP06, and Lactobacillus rhamnosus WKA55. This solution aims to protect the liver and effectively mitigate alcohol-related harm while allowing drinkers to enjoy themselves.

Alcohol Elimination - Bacillus coagulans BC99

Through research, it has been found that ADH (alcohol dehydrogenase) and ALDH (aldehyde dehydrogenase) enzymes are identified in the protein composition of Bacillus coagulans BC99. Alcohol metabolism in the human body primarily depends on the metabolic detoxification enzymes in the liver (ADH and ALDH). ADH converts alcohol into carcinogenic acetaldehyde, which is further oxidized by ALDH into non-toxic acetic acid.

Source: Urtasun R, Díaz-Gómez J, Araña M, et al. A combination of apple vinegar drink with Bacillus coagulans ameliorates high fat diet-induced body weight gain, insulin resistance and hepatic steatosis[J]. Nutrients, 2020, 12(9): 2504.

Alleviating Ethanol-Induced Liver Injury - Pediococcus pentosaceus PP06

Pediococcus pentosaceus PP06 can increase microbial diversity and improve the decrease in short-chain fatty acids (SCFAs) caused by alcohol intake. Data shows that the modified gut microbiota, SCFAs, and intestinal barrier contribute to alleviating systemic inflammation and liver damage.

Source: Jiang X W, Li Y T, Ye J Z, et al. New strain of Pediococcus pentosaceus alleviates ethanol-induced liver injury by modulating the gut microbiota and short-chain fatty acid metabolism[J]. World Journal of Gastroenterology, 2020, 26(40): 6224.

Liver Fat Reduction and Protection - Lactobacillus rhamnosus WKA55

Lactobacillus rhamnosus WKA55 possesses strong free radical scavenging abilities, assisting in the removal of excess free radicals from the body and enhancing antioxidant capacity to reduce liver damage. Additionally, Lactobacillus rhamnosus WKA55 exhibits strong adhesion to intestinal epithelial cells, improving intestinal barrier function. Mouse experiments have shown that Lactobacillus rhamnosus WKA55 can reduce liver index values, improve liver swelling, inhibit serum transaminase activity caused by alcohol-induced liver damage, and significantly contribute to liver fat reduction and protection.

Source: Patent Application ZL202210479470.5 for the use and production of Lactobacillus rhamnosus WKA55 in the preparation of products for the prevention and treatment of alcoholic liver injury.

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WecSim® Probiotic Powder Scale Intelligent Manufacturing System

High Activity, High Stability - Quality Assurance

Our company has always adhered to the quality and technological development path without wavering. Focusing on the bottleneck problems in probiotic strain technology and industrialization, we have proposed a scale intelligent manufacturing strategy based on process optimization and constructed relevant manufacturing systems using modern intelligent control methods and technologies. We have independently developed and mastered the WecSim® Probiotic Powder Scale Intelligent Manufacturing System.

In the production process of WecPro® Hangover Liver Protection core strains, the WecSim® Probiotic Powder Scale Intelligent Manufacturing System optimizes the production and manufacturing process of probiotics from medium selection, process condition optimization, post-processing technology, protective agent screening, freeze-drying process optimization, etc. This ensures the high stability and activity of the strains. Through multiple small-scale trials, pilot tests, and mass production using industry-leading production facilities and supply chain systems, we fully guarantee product quality and ensure that each tablet of our end solution contains 10 billion CFUs (colony-forming units) of live bacteria. Our products undergo full traceability throughout the entire process.